Knee pain

What is knee pain?

Knee pain is discomfort, aching or soreness in and around the knee joint. It can affect one or both knees and may range from mild discomfort to pain that affects walking, exercise and everyday activities. Knee pain can develop suddenly after an injury or build gradually over time.

Many people experience knee pain due to overuse, strain or everyday wear and tear. However, ongoing or worsening knee pain may sometimes be linked to an underlying condition, such as arthritis, ligament injuries or inflammation.

Understanding what may be causing your knee pain is the first step to finding the right treatment and improving long-term mobility and joint health.

Where does knee pain occur?

Where you feel knee pain can help identify what’s causing it. Different structures in and around the knee are responsible for different areas of discomfort.

Location

Common causes

Front of the knee

Arthritis, bursitis, patellofemoral pain syndrome (runner’s knee)

Behind the knee

Tendon or ligament injuries, Baker’s cyst, arthritis

Inside edge

MCL injury, arthritis

Outside edge

LCL tears, iliotibial band syndrome, arthritis

How knee pain develops

Knee pain develops when the structures inside or around the knee become irritated, damaged or placed under repeated stress. The knee is a complex joint made up of bones, cartilage, ligaments, tendons and muscles that work together to support movement and absorb pressure.‍

Everyday activities such as walking, climbing stairs and exercise place regular strain on the knee joint, which can lead to wear and discomfort over time.‍

Knee pain can develop suddenly after an injury, such as twisting the knee, overstretching or a fall. In other cases, it may build gradually due to repetitive movement, overuse or age-related changes such as arthritis.

UK Vein Clinic - Man sitting holding knee

Signs and symptoms of knee pain

Common signs and symptoms

Knee pain symptoms can vary depending on the cause, but there are several common signs that may include:

  • Pain in or around the knee joint, which may be dull, sharp or aching
  • Swelling or inflammation around the knee
  • Stiffness, especially after rest or first thing in the morning
  • Reduced movement or difficulty bending and straightening the knee
  • Clicking, popping or grinding sensations in the joint
  • Weakness or instability, where the knee may feel like it could “give way”
  • Pain that worsens with activity such as walking, running or climbing stairs

Symptoms may develop gradually or appear suddenly after an injury. Some people find symptoms come and go, while others may notice that they gradually worsen over time.

When symptoms may worsen

Knee pain symptoms often vary and may become worse during certain activities or at particular times.

  • During or after physical activity such as walking, running or climbing stairs
  • After long periods of standing or sitting in one position
  • After rest or inactivity, when stiffness may be more noticeable
  • During cold or damp weather, which some people find increases discomfort
  • Following overuse or when the knee has not had enough time to recover after injury

Persistent or worsening symptoms may sometimes suggest an underlying condition and should be assessed if they begin affecting daily activities.

UK Vein Clinic - Man sitting holding knee

Causes and risk factors

Common causes

Knee pain can develop for a range of reasons and is often linked to injury, overuse or gradual wear and tear over time. The underlying cause can affect how symptoms develop and which treatment options may be most appropriate.

  • Osteoarthritis: Wear and tear of the joint over time, leading to stiffness, pain and reduced movement.
  • Ligament injuries: Sprains or tears caused by twisting or sudden movement, often during sport.
  • Cartilage (meniscus) damage: Injury to the cushioning inside the knee, usually from twisting or impact.
  • Tendonitis: Inflammation of the tendons caused by overuse or repetitive strain.
  • Bursitis: Inflammation of the small fluid-filled sacs around the knee joint.
  • Overuse or strain: Repetitive activity or high-impact movement can place extra stress on the knee over time.
  • Neovascularisation: Inin some long-term joint conditions, ongoing inflammation can lead to tiny new blood vessels forming in the joint lining. This can make the knee more sensitive and may contribute to ongoing pain and stiffness.

Risk factors you should know

Several factors raise your chances of developing knee pain:

  • Age: Knee joints naturally wear over time, increasing the risk of pain.
  • Excess weight: Extra pressure on the knees can increase strain and discomfort.
  • Previous injury: Past knee injuries can make the joint more vulnerable to future pain.
  • Physical activity or job strain: Repetitive movements, kneeling or heavy use of the knees can increase wear.
  • Low activity levels: Weak muscles around the knee can reduce joint support.

How knee pain is diagnosed

Oxford Knee Score (knee pain assessment)

If your leg pain is related to knee pain or knee osteoarthritis, your doctor may use the Oxford Knee Score as part of your assessment.

This short questionnaire looks at how knee symptoms affect everyday activities such as walking, climbing stairs, standing up from a chair and getting dressed. It also measures pain levels and how well the knee is functioning.

The results can help to:

  • Measure how severe knee symptoms are
  • Understand how symptoms affect daily life
  • Monitor changes over time
  • Support treatment decisions and assess response to treatment

"When leg pain is linked to the knee, the Oxford Knee Score helps measure how symptoms impact everyday activities such as walking, climbing stairs and mobility. This gives a clearer picture of how the condition is affecting the patient as a whole."

Antoni Otto

Vascular Doctor at UK Vein Clinic

Diagnostic tests

In many cases, knee pain can be diagnosed through symptoms, medical history and a physical examination. However, if the cause is unclear or symptoms continue, further tests may be recommended.

  • X-ray: Often used to check for arthritis, joint damage or changes in bone structure. 
  • MRI scan: Produces detailed images of ligaments, cartilage and tendons, helping identify soft tissue injuries. 
  • CT scan: creates detailed cross-sectional images of the body, helping assess bone structure and more complex joint problems
  • Ultrasound scan: Can assess inflammation and soft tissue structures around the knee in real time. 
  • Blood tests: May help identify inflammatory conditions or infection. 
UK Vein Clinic - doctor analysing knee image

Treatment options for knee pain

Lifestyle changes and self-care

Many people with knee pain can improve their symptoms with simple lifestyle changes and self-care at home. These are often recommended as the first step, particularly for mild to moderate knee pain. 

  • Stay active: Gentle exercise such as walking, swimming or cycling can help keep the knee joint mobile and reduce stiffness.
  • Strength and support: Strengthening the muscles around the knee can improve stability and reduce pressure on the joint.
  • Weight management: Maintaining a healthy weight can reduce strain on the knees and help ease symptoms over time.
  • Cold or heat packs: Ice can help reduce swelling, while heat may ease stiffness and improve comfort.
  • Pain relief: Over-the-counter pain relief may help manage short-term discomfort if suitable for you.

While these approaches can help manage symptoms, they may not always provide enough relief for ongoing or more severe knee pain, particularly when inflammation associated with osteoarthritis is involved.

Embolisation treatment (Genicular Artery Embolisation) 

For people with persistent knee pain, particularly linked to osteoarthritis, a minimally invasive treatment called genicular artery embolisation (GAE) may be considered. 

Embolisation treatment works by targeting the small blood vessels supplying inflamed areas of the knee joint. During the procedure, a specialist inserts a thin catheter, usually through the wrist or groin, and delivers tiny particles to reduce blood flow to these vessels. This can help reduce inflammation, ease pain and improve mobility over time. 

The procedure does not involve open surgery, and most patients are able to go home the same day. GAE is typically considered when symptoms have not improved with treatments such as physiotherapy, pain relief or lifestyle changes.

Physiotherapy

Physiotherapy is often used to help manage knee pain by improving strength, movement and stability around the joint.

  • Strengthening exercises: Build support around the knee to reduce strain on the joint
  • Stretching: Helps improve flexibility and reduce stiffness
  • Movement advice: Guidance on walking, stairs and daily activity to reduce pain triggers
  • Practical support: Advice on posture, footwear and activity levels

Physiotherapy aims to reduce pain and improve long-term knee function.

UK Vein Clinic = phisiotherapy session

Medications

If self-care and physiotherapy are not enough to control knee pain, your GP may recommend medication to help manage symptoms and improve comfort.

  • Simple pain relief: Such as paracetamol to help reduce pain levels
  • Anti-inflammatory medicines: NSAIDs may be used to help reduce pain and swelling in the joint
  • Stronger pain relief: In some cases, short-term stronger painkillers may be prescribed for more severe symptoms 
  • Topical treatments: Pain-relieving gels or creams applied directly to the knee can help ease local discomfort 

Medication is usually used alongside other treatments, rather than on its own, to help improve mobility and support recovery. 

Procedures

If knee pain is ongoing or not improving with self-care, physiotherapy or medication, further procedures may sometimes be considered depending on the underlying cause.

These may include:

  • Genicular artery embolisation (GAE): A minimally invasive procedure that targets blood vessels contributing to inflammation in the knee to help reduce pain and improve mobility.
  • Steroid injections: May be used to help reduce inflammation and provide temporary symptom relief.
  • Joint injections: Certain injections may help improve lubrication within the joint and reduce discomfort in some patients.
  • Knee replacement surgery: In more severe cases, surgery may be considered when symptoms significantly affect daily activities and other treatments have not provided enough relief.

Can knee pain be prevented?

Knee pain cannot always be fully prevented, especially when it is linked to ageing or natural wear and tear. However, risk can be reduced by staying active, maintaining a healthy weight, and doing regular low-impact exercise such as walking or swimming.

Strengthening the muscles around the knee, wearing supportive footwear, and avoiding overuse can also help protect the joint and reduce the chance of ongoing pain.

Reducing your risks

There are several simple steps that can help reduce the risk of developing knee pain or prevent symptoms from getting worse.

  • Stay active: Regular low-impact exercise helps keep the knee joint flexible and supported.
  • Strengthen muscles: Exercises that build strength in the legs and hips can reduce pressure on the knee.
  • Maintain a healthy weight: This helps lower stress placed on the knee joints during movement. 
  • Wear supportive footwear: Good shoes can help improve alignment and reduce impact on the knees.

Taking early action can help protect knee health and reduce the chance of long-term pain.

When to seek medical advice

Signs you shouldn't ignore

Contact your GP or emergency services if you experience:

  • Sudden or severe knee pain, especially after injury
  • Swelling that does not improve or keeps returning
  • Redness, warmth or tenderness around the joint
  • Locking, instability or the knee giving way
  • Pain that is not improving after a few weeks

Early assessment ensures that any serious causes are ruled out and that you get the right treatment quickly.

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