Leg pain

What is leg pain?

Leg pain is a common symptom that can affect the muscles, joints, nerves, or blood vessels in the leg. It can feel like aching, heaviness, cramping, or sharp pain, and may start suddenly or develop gradually over time.

There are many possible causes of leg pain, including overuse, injury, joint conditions such as knee problems, or circulation issues affecting the veins and arteries. In some cases, it may be linked to underlying conditions that need medical assessment, especially if the pain is persistent, worsening, or affecting everyday movement. 

Understanding what may be causing your leg pain is the first step to finding the right treatment. If symptoms are linked to knee problems, assessment tools such as the Oxford Knee Score can help measure how pain affects movement and everyday activities.

When is leg pain an emergency?

Some causes of leg pain need urgent medical attention. Go to A&E or call 999 immediately if you experience:

  • Sudden swelling, redness, warmth or pain in one calf or leg — these may be signs of deep vein thrombosis (DVT), a blood clot that can be life-threatening if untreated
  • Severe leg pain after a fall or injury, particularly if you cannot bear weight
  • Chest pain, breathlessness, or coughing up blood alongside leg swelling, possible signs of a pulmonary embolism (PE)

If pain is not immediately urgent but is persistent, worsening, or affecting daily life, contact your GP.

How leg pain develops

Common signs and symptoms

Leg pain develops when the normal function of muscles, joints, nerves or circulation in the legs is affected. Symptoms can appear suddenly after an injury or build gradually over time depending on the underlying cause.

This can happen for several reasons:

  • Injury to muscles, tendons or joints
  • Overuse or strain from physical activity
  • Long-term wear and tear in the knee or lower limb joints
  • Pressure on nerves, which can cause pain, tingling or weakness
  • Reduced blood flow or circulation issues affecting the legs and veins
UK Vein Clinic - leg pain

Who is affected?

Common causes

Leg pain is very common and can affect people of all ages, but some groups are more likely to develop ongoing symptoms.It is often linked to circulation problems, nerve irritation, muscle strain, or vein conditions. 

Higher-risk groups include: 

  • Adults over 40: higher risk of vein and joint-related changes
  • People who sit or stand for long periods: reduced blood flow in the legs
  • People who are overweight: extra pressure on joints and veins
  • Pregnant women: increased pressure on leg veins
  • People with circulation problems: such as venous or arterial conditions
  • People with previous injuries or back issues: including sciatica

Persistent leg pain, especially when linked with swelling, heaviness, or skin changes, should be assessed to identify the underlying cause.

Signs and symptoms of leg pain

Common signs and symptoms

Leg pain can feel different depending on the cause, and may range from mild discomfort to more severe, ongoing pain. It may come on suddenly or develop slowly over time.Leg pain can feel different depending on the cause, and may range from mild discomfort to more severe, ongoing pain. It may come on suddenly or develop slowly over time.

Common signs and symptoms include:

  • Aching or heaviness in the legs, often worse at the end of the day
  • Throbbing or burning pain, especially in the calves or thighs
  • Cramping, particularly at night or after activity
  • Swelling in the lower legs, ankles or knees
  • Tingling or numbness, which may suggest nerve involvement
  • Visible veins or varicose veins, which can be linked with discomfort
  • Pain that worsens when standing or sitting for long periods
  • Relief when walking or elevating the legs, in some circulation-related cases

When symptoms may worsen

Leg pain can vary throughout the day and often becomes more noticeable depending on activity and circulation. Symptoms may worsen: 

  • At the end of the day, after long periods of standing or sittingIn warm weather, as blood vessels expand
  • During pregnancy, due to increased pressure on leg veins
  • After long periods of inactivity, such as travel or desk work
  • After exercise or strain, especially if muscles are overused
UK Vein Clinic - leg pain while exercising

Causes and risk factors

Common causes

Leg pain often develops due to problems affecting the veins, muscles, nerves, or joints. In many cases, more than one factor may be involved.

Common causes include:

  • Varicose veins and chronic venous insufficiency: weakened vein valves allow blood to pool in the legs, leading to aching, heaviness, and discomfort
  • Muscle strain or overuse: caused by exercise, lifting, or sudden increases in activity
  • Nerve-related pain (such as sciatica): irritation or compression of nerves can cause pain that travels down the leg
  • Poor circulation: reduced blood flow can lead to cramping, especially when walking
  • Joint conditions (such as osteoarthritis): Wear and tear affecting the hips or knees can cause leg pain and affect daily activities such as walking, climbing stairs and getting up from a chair. 
  • Minor injuries: sprains, knocks, or soft tissue damage
  • Pain that may spread from the knee, hip or lower back into the leg
  • Chronic inflammation in joints: ongoing inflammation can lead to tiny new blood vessels forming around the joint lining leading to synovial vascularisation. Causing sensitivity and ongoing aching, stiffness, and leg discomfort.
  • Deep vein thrombosis (DVT): a blood clot forming in a deep vein of the leg, causing sudden pain, swelling, redness and warmth — usually in one leg. DVT requires urgent medical assessment.

Risk factors you should know

Several factors can increase your risk of developing ongoing leg pain, particularly when linked to vein or circulation problems:

  • Prolonged standing or sitting: reduces efficient blood flow in the legs
  • Increasing age: vein valves and joints naturally weaken over time
  • Being overweight: adds pressure to the veins and lower limbs 
  • Pregnancy: increases pressure on pelvic and leg veins
  • Family history of vein disease: such as varicose veins 
  • Low activity levels: can slow circulation and weaken muscle support

Understanding these risk factors can help identify why leg pain develops and when it may be linked to an underlying vein condition.

Pain in one leg vs pain in both legs

Whether pain affects one leg or both is an important clue to the underlying cause.

Pain in one leg is more often linked to localised problems such as:

  • Deep vein thrombosis (DVT) — sudden swelling, redness and warmth in one calf
  • Muscle strain or injury from overuse or trauma
  • A trapped or compressed nerve, such as sciatica affecting one side
  • Peripheral arterial disease (PAD) causing cramping in one leg when walking

Pain in both legs is more commonly associated with:

  • Chronic venous insufficiency or varicose veins — causing bilateral aching and heaviness
  • Nerve conditions such as peripheral neuropathy
  • Muscle cramps, often occurring at night
  • Systemic conditions such as arthritis affecting multiple joints

If you have sudden pain in one leg with swelling and warmth in the calf, seek urgent medical advice to rule out DVT.

How leg pain is diagnosed

Leg pain is diagnosed by a doctor through a combination of symptom assessment, medical history, and physical examination. Where knee pain is involved, specific scoring systems and questionnaires may also be used to help measure the severity of symptoms and how they affect daily life. 

These tools help doctors understand:

  • How severe your symptoms are
  • How pain is affecting movement and function
  • Whether symptoms are improving or worsening over time
  • Which treatment options may be most appropriate

“A thorough assessment is essential in identifying the underlying cause of leg pain. Once the cause is understood, treatment can be targeted more effectively and tailored to the individual patient.”

Alina Roser

Vascular Doctor at UK Vein Clinic

Clinical examination

When assessing different causes of leg pain, a physical examination helps identify whether symptoms are linked to veins, muscles, joints, or nerves.

This may include:

  • Checking for swelling, varicose veins, or skin changes
  • Assessing movement, strength, and walking pattern
  • Testing circulation in the legs and feet
  • Identifying areas of tenderness or discomfort

This helps determine whether the pain is linked to veins, muscles, joints, or nerves, and whether further tests are needed.

Other tools and assessments may also be used to understand your symptoms in more detail. One commonly used tool is the Numerical Rating Scale (NRS), which asks you to rate your pain from 0 to 10, with 0 meaning no pain and 10 meaning the worst pain imaginable. Your doctor may use this score to assess the severity of your symptoms, compare pain levels between visits, and monitor whether treatments are improving your condition. 

The Numerical Rating Scale can also help identify how pain changes throughout the day or during specific activities, such as walking, standing, exercising, or resting. Combined with your medical history and physical examination findings, it provides valuable information that helps guide diagnosis, treatment decisions, and ongoing management of leg pain.

UK Vein Clinic - doctor pointing to leg model

Diagnostic tests

If the cause of leg pain is not clear, or symptoms continue, further tests may be needed to confirm the diagnosis and guide treatment:

  • Duplex ultrasound: the main test used to assess vein function and identify varicose veins or venous insufficiency
  • Ankle-brachial pressure index (ABPI): checks blood flow in the legs and helps detect circulation problems
  • X-rays: used to look for joint or bone issues such as arthritis or injury
  • MRI scan: provides detailed images of soft tissues, including muscles, nerves, and spinal structures, often used when nerve-related pain is suspected 
  • CT scan: may be used when more detailed imaging is needed of bones or internal structures
  • Nerve conduction studies / EMG: used to assess nerve function and help identify nerve damage or compression 

Treatment options for leg pain

Lifestyle changes and self-care

Many people who suffer with leg pain can improve their symptoms significantly through changes such as:

  • Staying active: gentle exercise such as walking or swimming helps improve blood flow and reduce stiffness
  • Avoid long periods of sitting or standing: regular movement helps prevent blood from pooling in the legs
  • Leg elevation: raising the legs can help reduce swelling and heaviness
  • Healthy weight management: reduces pressure on the legs and veins
  • Compression stockings: may be recommended for vein-related symptoms such as aching or swelling
UK Vein Clinic - person running/exercising

Physiotherapy

Physiotherapy can be helpful when leg pain is linked to muscles, joints, or nerve irritation. A tailored programme may include:

  • Targeted exercises: stretching and strengthening to improve mobility and support the lower limbs
  • Movement and posture advice: to reduce strain on the back, hips, knees, and legs
  • Strength building: improving muscle support to reduce pressure on affected areas
  • Activity guidance: helping patients return to normal movement safely

For people with knee-related leg pain, improvements in symptoms and mobility may also be monitored using tools such as the Oxford Knee Score.

Medications

If leg pain is ongoing or linked to an underlying condition, different types of medication may be used to help manage symptoms while the cause is treated.

  • Over-the-counter pain relief: such as paracetamol or ibuprofen may help short-term pain and discomfort
  • Neuropathic pain medicines: such as amitriptyline, gabapentin, or pregabalin may be used for nerve-related pain
  • Anti-inflammatory medicines (NSAIDs): such as ibuprofen or diclofenac may be used to reduce pain and inflammation, particularly for joint or soft tissue conditions
  • Circulation-related medicines: such as antiplatelet medicines (e.g. aspirin or clopidogrel) or statins may be used in arterial disease to improve blood flow and reduce risk factors
  • Steroid injections: may sometimes be used for joint conditions such as knee osteoarthritis to reduce inflammation and pain. They can provide short-term relief, but the effects are usually temporary and they are not considered a long-term solution.

Medication is usually most effective when used alongside lifestyle changes, physiotherapy, or targeted treatment for the underlying cause of leg pain.

Minimally invasive procedures

If leg pain is severe or not improving with other treatments, further procedures may be recommended depending on the cause.

These treatments are usually done without open surgery and often allow a quicker recovery.

These may include:

  • Embolisation: blocks abnormal blood flow in targeted veins to reduce pressure and symptoms
  • Endovenous radiofrequency ablation (EVRF): uses heat to close affected varicose veins and improve circulation
  • Foam sclerotherapy: a medical foam is injected into the vein to seal it and redirect blood flow

These procedures are usually only considered when leg pain is persistent, worsening, and not responding to conservative treatments.

Surgical procedures 

In some cases, surgery may be needed if symptoms are severe or other treatments have not worked.

These may include:

  • Vein stripping and ligation: used for larger or more extensive varicose veins when minimally invasive treatments are not suitable or have not worked
  • Ambulatory phlebectomy: used to remove smaller surface varicose veins that are close to the skin and causing discomfort or visible bulging
  • Endarterectomy: used when arteries are narrowed by fatty build-up, reducing blood flow and causing pain when walking (claudication)
  • Bypass surgery: used when arteries are severely blocked and blood flow is significantly reduced, creating a new route for blood to travel around the blockage
  • Angioplasty (with or without a stent): used to open narrowed or blocked arteries in the leg to improve blood flow and reduce pain when walking (claudication)

Treatments for bone health and joint conditions 

If leg pain is linked to bone or joint conditions, treatment may focus on improving joint health and slowing progression. 

This may include:

  • Physiotherapy: exercises to improve strength, flexibility, and movement
  • Weight management support: to reduce pressure on joints such as the knees and hips
  • Pain relief and anti-inflammatory medication: to help manage symptoms
  • Joint injections: such as corticosteroid injections for short-term relief in osteoarthritis
  • Bone-strengthening medication: such as bisphosphonates, used in conditions like osteoporosis to reduce fracture risk

Can leg pain be prevented?

Not all leg pain can be prevented, but there are simple steps that can help reduce the risk. Staying active, avoiding long periods of sitting or standing, maintaining a healthy weight, and supporting good circulation can all help keep the legs healthy. Wearing compression stockings when advised and treating any vein or circulation problems early may also help prevent symptoms from developing or getting worse over time.

Reducing your risks

While not all leg pain can be prevented, these habits lower your chances:

  • Stay active with regular walking or gentle exercise 
  • Avoid sitting or standing in one position for long periods
  • Maintain a healthy weight to reduce pressure on veins and joints
  • Elevate your legs when resting to improve blood flow 
  • Wear compression stockings if recommended 
  • Treat vein or circulation problems early to prevent symptoms from worsening

When to seek medical advice

Red flag symptoms of leg pain

Contact your GP or emergency services if you experience:

  • Sudden or severe leg pain with no clear cause
  • Swelling, redness, or warmth in one leg - these may be signs of deep vein thrombosis (DVT). Call 999 or go to A&E immediately 
  • Pain that gets worse when walking or does not improve with rest
  • Visible veins with increasing discomfort or heaviness
  • Skin changes such as discolouration, hardening, or ulcers
  • Ongoing leg pain that is affecting daily activities or sleep

These symptoms may suggest an underlying vein or circulation problem that needs assessment and treatment.

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Varicose veins can be painful and make it difficult to exercise and be active

Where to find us

We're pleased to be able to provide our world-class varicose vein treatment in a variety of places throughout the United Kingdom. Learn more about your treatment options, including endovenous radio-frequency ablation (EVRF) and foam sclerotherapy, at the clinic closest to you.